TRANSCUTANEOUS ANALYTE MEASURING METHODS (TAMM)

TAMM RELATES TO TWO TECHNOLOGIES FOR NONINVASIVE TRANSCUTANEOUS MEASUREMENTS OF BLOOD ANALYTES THAT HAVE POTENTIAL FOR APPLICATION IN A COMBAT CASUALTY CARE ENVIRONMENT. THE NEAR INFRARED (NIR) REFLECTANCE TECHNOLOGY DETERMINES BLOOD ANALYTE CONCENTRATION BASED ON DIFFUSE REFLECTANCE MEASUREMENTS WITH A FIBER OPTIC PROBE. SPECTRAL DATA ACQUIRED IS PROCESSED USING SOPHISTICATED PATTERN RECOGNITION TECHNIQUES TO DETERMINE CHEMICAL CONCENTRATION. THE SECOND TECHNOLOGY, REFLECTIVE FLUORESCENCE, USES A SIMILAR FIBER OPTIC PROBLE BUT WITH DIFFERENT INSTRUMENTATION TO MEASURE LUMINESCENCE IN THE EPIDERMIS GENERATED BY PRIMARY OR SECONDARY FLUORESCENCE OF BLOOD ANALYTES. BIOTRONICS' PREVIOUS INSTRUMENTATION DEVELOPMENTS AND CLINICAL EXPERIENCE WILL SUPPORT THE EXPEDITIOUS EVALUATION OF THESE TECHNOLOGIES AND OFFER THE POTENTIAL FOR SUCCESS IN MILITARY FIELD APPLICATIONS. THIS POTENTIAL IS AUGMENTED BY BIOTRONICS' PROVEN RECORD IN THE DEVELOPMENT AND PRODUCTION OF SMALL, RUGGED CLINICAL INSTRUMENTS.