SBIR/STTR Research Award

CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH

Award identifier 2c32b56da763b8eb72bb5c4796281bc217bf53309053f6dc36f80921a91a8b77Awarding agency Department of Health and Human Services

Award amount

$50,000

Program and phase

SBIR · Phase I

Award year

1988

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
Peptide Technolgies Corp.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

A NEW COUNTERCURRENT CHROMATOGRAPHY INSTRUMENT, THE CROSS-AXIS, FLOW-THROUGH COIL PLANET CETRIFUGE, WHICH IS EQUIPPED WITH ECCENTRICALLY ORIENTED MULTILAYER COILS, IS PROPOSED FOR THE PREPARATIVE CHROMATOGRAPHY OF PEPTIDES. THIS IS AN APPARATUS THAT SEPARATES SUBSTANCES ACCORDING TO THEIR PARTITIONING IN A LIQUID-LIQUID EQUILIBRATION SYSTEM WITHOUT THE USE OF A SOLID-PHASE SUPPORT. THE INSTRUMENT WILL BE TESTED IN THE PURIFICATION OF LARGE QUANTITIES OF SYNTHETIC PEPTIDES, USING DIFFERENT CONDITIONS AND SOLVENT SYSTEMS TO ACHIEVE HIGH RESOLUTION AND RECOVERY. THE SUCCESSFUL DEVELOPMENT OF THIS INSTRUMENT WOULD MAKE AVAILABLE A LOWER COST TECHNOLOGY FOR CHROMATOGRAPHIC PURIFICATION.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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