SBIR/STTR Research Award
THE LONG-TERM GOAL OF THIS PROJECT IS THE DEVELOPMENT OF NEWTHERAPEUTIC STRATEGIES FOR THE CIRCUMVENTION OF DRUG RESISTANCE IN HUMAN NEOPLASMS.
Award amount
$50,000Program and phase
SBIR · Phase IAward year
1986Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- ONCOTECH, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
THE LONG-TERM GOAL OF THIS PROJECT IS THE DEVELOPMENT OF NEWTHERAPEUTIC STRATEGIES FOR THE CIRCUMVENTION OF DRUG RESISTANCE IN HUMAN NEOPLASMS. BY FIRST ESTABLISHING THE ABILITY OF THE DIFFERENTIAL STAINING CYTOTOXICITY ASSAY TO DETECT AND CIRCUMVENT DRUG RESISTANCE, THE PROJECT WILL LAY THE FOUNDATION FOR CLINICAL TRIALS DESIGNED TO APPLY INDIVIDUALIZED REGIMENS FOR THE EFFECTIVE TREATMENT OF REFRACTORY HUMAN MALIGNANCIES. THERAPIES WILL BE DESIGNED TO INCORPORATE SYNERGISTIC INTERACTIONS BETWEEN CYTOTOXIC AND NON-CYTOTOXIC AGENTS AND TO PROVIDE MAXIMAL PROTECTION TO NORMAL TISSUES. THE ULTIMATE GOAL WILL BE TO EXPAND THESE STUDIES INTO COOPERATIVE CLINICAL TRIALS AND TO REFINETHE TECHNIQUES AND EQUIPMENT USED FOR EVENTUAL DISSEMINATIONTO THE ONCOLOGIC COMMUNITY AT LARGE.
Technology keywords
Not reported