SBIR/STTR Research Award
DEVELOPMENT OF ALTERNATIVE AFFINITY CAPTURE REAGENTS FOR CANCE
Award amount
$149,857Program and phase
SBIR · Phase IAward year
2010Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- NECTAGEN INC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- KAFMLCY56WM3
- Solicitation number
- PHS2010-1
- Topic code
- NCI
Research abstract
Many of the antibodies produced for cancer research are poorly characterized, exhibit suboptimal affinity or selectivity, and are time-consuming and expensive to produce. Alternative affinity capture reagents are therefore needed as reproducible, highly characterized, rapid, and cost-effective substitutes for monoclonal antibodies. As a platform for creating affinity capture reagents, Aptakon has developed a 10 kD protein scaffold with loops similar to the complementarity determining region of the immunoglobulin domain. Aptakon aims to construct plasmid and phagemid libraries of variant scaffolds
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Development of Custom nanoCLAMP Affinity Chromatography Resins for Fast, Efficient Purification of Plasma Proteins
- Development of an Orally Available Therapeutic for Neutralizing C. difficile Toxin B
- Development of DNA-Labeled Antibody Mimetics as Low-Cost, High-Performance Reagents for Single Cell Analysis of Membrane Proteins
- Development of Enzyme Replacement Therapy for Complement C2-Deficiency
- Affinity reagents for the sub-fractionation of specific exosomal populations
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment
- Development of small molecule therapeutics targeting AR-V7 for prostate cancer
- Decentralized Clinical Trial of Effectiveness of EnergyPoints App to Guide Acupressure Use for Fatigue and Sleep Disturbances in Cancer Survivors
- Optimized targeted radiotherapy of pancreatic cancer
- Adaptive imaging for pioneering multiplexed spatial profiling of tumors and tissues for cancer research and diagnosis
Research funding history
9 SBIR/STTR records share this UEI (2010–2024). Reported award amounts total $1,649,265. Reported amounts are not federal obligations.
Phases: Phase I
Agencies: Department of Health and Human Services