SBIR/STTR Research Award

A Novel Caries Prevention and Treatment System

Award identifier 6df055424937d8c31eca6465e3af5913770c4a54307e900b9a34e0b379b4fc53Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$137,018

Program and phase

SBIR · Phase I

Award year

2006

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
CREARE LLC
Proposal award date
Not reported
Contract end date
Not reported
UEI
JDKYAKDT4TT6
Solicitation number
PHS2006-2
Topic code
Not reported

Research abstract

DESCRIPTION (provided by applicant): The specific aim of this research program is the development of a low-cost, laser-based caries prevention and treatment system to effectively reduce or eliminate caries in children and adults. Even with the substantial decline in caries that has occurred over the last several decades, a substantial percentage of children and adults have evidence of untreated caries in their permanent teeth. Furthermore, the decline in caries reached a plateau during the 1990s. Many methods are currently available for caries prevention and treatment. However, they are limited by their high cost, limited availability or effectiveness, or lack of long- term caries resistance. Hence, new approaches are needed to address these key issues and provide a low- cost, long-term solution that can prevent caries altogether. Creare's innovation is the Caries Prevention and Treatment System (CRTS). This novel system combines a standard fluoride treatment with a low-power, low-cost, continuous-wave laser to almost completely inhibit enamel demineralization. Novel methodologies to measure the real-time enamel temperature will be integral to the system. This hardware will be combined with model-based adaptive control software to precisely control the enamel temperature. In so doing, our innovation will maximize the effectiveness of treatment while improving ease of use and eliminating the risk of damage to sensitive tissues. The low cost of our innovation will enable increased access to critical caries management and treatment, which is of particular importance to high-risk children and adults. Our novel system will improve the affordability, access, effectiveness, practicality, and safety of caries prevention.

Technology keywords

Not reported

Research funding history

1,365 SBIR/STTR records share this UEI (1983–2026). Reported award amounts total $507,020,394. Reported amounts are not federal obligations.

Phases: Phase I, Phase II, Phase II – Direct to Phase II

Agencies: Department of Defense, National Aeronautics and Space Administration, Department of Health and Human Services, Department of Energy, Department of Transportation, Department of Commerce

Agency intelligence

Department of Health and Human Services

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