SBIR/STTR Research Award

Development of a Novel Agent for Alcohol Dependence

Award identifier d8f38c692e7a8c4b202f1ff1b0be36b225e9d8327903e842270bdf13988357aaAwarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$115,007

Program and phase

SBIR · Phase I

Award year

2003

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
THIOPHARMA, INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

DESCRIPTION (provided by applicant): Studies are proposed to complete the development of S-methyl N, Ndiethylthiolcarbamate sulfoxide (DETC-MeSO), a novel agents for the treatment of alcohol dependence. Specifically the following studies will be performed. 1. Complete the process chemistry development for DETC-MeSO and its Isomers. (carried out at Thiopharma, Inc) 2. Synthesize sufficient scale UP quantities for preclinical toxicology studies. (carried out at Pharm-Eco Laboratories, Inc) 3. Carry out pharmacokinetic studies in rats to support preclinical toxicology studies. (carried out at The University of Kansas) 4. Preclinical toxicology studies in rats and dogs. (carried out at Battelle).

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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