SBIR/STTR Research Award
RAPID FIBRINOGEN ASSAY FOR USE IN THROMBOLYTIC THERAPY
Award amount
$500,000Program and phase
SBIR · Phase IIAward year
1992Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Biotherm, Inc.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
AN ASSAY SYSTEM FOR MONITORING FUNCTIONAL FIBRINOGEN IN PATIENTS UNDERGOING THROMBOLYTIC THERAPY WILL BE DEVELOPED. THIS SYSTEM WILL BE BASED ON A NOVEL DRY REAGENT ASSAY TECHNOLOGY THAT HAS RECENTLY BEEN APPLIED SUCCESSFULLY TO PTAND ACTIVATED PTT TESTS. INTRODUCTION OF A RAPID, CONVENIENT, FIBRINOGEN ASSAY SYSTEM ON A DECENTRALIZED BASISCOULD PROVIDE ACCURATE RESULTS SOONER THAN EXISTING LABORATORY METHODS AND COULD SERVE AS AN IMPORTANT DIAGNOSTIC GUIDE IN THROMBOLYTIC THERAPY. THIS PROJECT WILL DEVELOP THIS FIBRINOGEN ASSAY SYSTEM AND ASSESS ITS POTENTIAL, USING A COMBINATION OF LABORATORY STUDIES OF INFLUENCING FACTORS AND CLINICAL SAMPLE STUDIES. APPLICATION TO EARLY DETERMINATION OF LOW FIBRINOGEN LEVELS IN THROMBOLYTIC THERAPY PATIENTS WILL BE EXPLORED. THIS WORK WILL BE PERFORMED IN CONJUNCTION WITH DUKE UNIVERSITY MEDICAL CENTER.
Technology keywords
Not reported