COCHLEATE DRUG DELIVERY AGAINST FUNGAL INFECTIONS

Not Available We propose to synthesize modem techniques of image analysis with the existing knowledge of concrete deterioration and failure processes in order to develop a comprehensive and efficient basis for quantitative microscopic analysis of the damage mechanisms in concrete. The focus of this research is on microstructural attributes which best characterize damage mechanisms in concrete; these include: (1) the volume, spatial distribution, networking, tortuosity, orientation, number, width and spacing of microcracks and cracks; (2) volume, spatial distribution, number, continuity, shape and size of voids; and (3) contiguity relationships of microcracks, cracks, voids, aggregates, and aggregate-paste interfaces. The following objectives are proposed to be accomplished in Phase I research: (1) identify the quantifiable micro structural features which reflect on prevalent damage mechanisms; (2) select image analysis and statistics principles and tools for evaluation of the quantifiable features; (3) develop a sampling plan for quantification and statistical inference of microstructural damage; (4) select suitable sample preparation and microscopy techniques; (5) experimentally verify the approach; and (6) devise an integrated computer-based system dedicated to the implementation of the new approach to micro structural damage quantification of concrete.