SBIR/STTR Research Award
Microarray chips for rapid detection of high affinity nucleic acid sequences
Award amount
$112,494Program and phase
SBIR · Phase IAward year
2006Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- APTAMATRIX, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- P6QQJF456L83
- Solicitation number
- PHS2006-2
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by applicant): This phase I project aims at demonstrating a method to rapidly discover short sequences that bind tightly to protein targets. Our plan in phase I is limited to proof of principle by screening against fluorescently tagged proteins, which will facilitate analysis. In phase II label-free detection methods of analysis will be pursued in an effort to generalizes the screening method. Oligonucleotides discovered in these screens can be engineered into sensors having exquisite sensitivity and selectivity for diagnostics and drug discovery applications.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Proteomic Analysis of Blood Plasma using High Throughput Sequencers
- Efficient Characterization of DNA-Protein Binding using a High-Throughput Sequencer
- Nanosensor Switches for Detection of Toxins, Pathogens, and Small Molecules
- Aptamer probes for Epigenetic Peptide Targets
- Simple DNA/RNA Probes for Protein Targets
Research funding history
11 SBIR/STTR records share this UEI (2003–2020). Reported award amounts total $6,277,598. Reported amounts are not federal obligations.
Phases: Phase I, Phase II, Phase II – Direct to Phase II
Agencies: Department of Health and Human Services, Department of Defense, Department of Homeland Security