SBIR/STTR Research Award

Novel membrane to link SDS-PAGE with mass spectrometry for proteomic studies of d

Award identifier 2bb0cd4d471fa6b9542d4fda46f59a0f3e7f96a02d0ef780b3a45d9158d90578Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$130,432

Program and phase

SBIR · Phase I

Award year

2014

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
VIRGIN INSTRUMENTS CORPORATION
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
PA11-215
Topic code
NIGMS

Research abstract

DESCRIPTION (provided by applicant): The objective of this proposal is to introduce a product that will enable protein separations by gel electrophoresis (SDS-PAGE) to be analyzed as peptides by mass spectrometry in an efficient, high-throughput manner. Such a device will offer investigators in biology and medicine a compelling new method for analyzing complex proteomic samples (100s - 1000s of individual components) by directly addressing the most persistent challenges in proteomic research; how to managesample component diversity, in both number and concentration, to maximize sample species detection while preserving information pertinent to the biology of the system. Availability of the product resulting from this work will address these challenges by coupling the most efficient, highest resolution, protein separation technique with the accuracy, sensitivity and speed of mass spectrometry detection of peptides in a manner that is thorough. Presently, this link does not exist. Subtle details in the v

Technology keywords

Not reported

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Agency intelligence

Department of Health and Human Services

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