SBIR/STTR Research Award
Asymmetric Syntheses of Carbon 13 Labeled Amino Acids.
Award amount
$691,949Program and phase
SBIR · Phase IIAward year
1996Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Le Research, Inc.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
New production methods for stable-isotope labeled amino acids that are suitable for NMR structuralmembrane proteins were identified as necessary for further advances in this field. Phase I aims to eSchoellkopf's lactim alkylation method for commercial L-tyrosine-3-13C, L-leucine-4-13C, and possibl13C. Preparation of the requisite labeled moieties are pursued using some new labeled reagents and rdeveloped. Should the method prove viable, Phase II will develop the preparative steps for other unkof common proteinogenic amino acids.
Technology keywords
Not reported