SBIR/STTR Research Award

NEW HPLC SUPPORTS FOR BIOCHEMICAL PURIFICATIONS

Award identifier 2e0de338d315f4de4dd5902f065a5cd1c44eef169c1059e510aa5cbce3148dedAwarding agency Department of Health and Human Services

Award amount

$47,625

Program and phase

SBIR · Phase I

Award year

1992

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
Wilhelmy Fine Particles
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

NEW HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC (HPLC) SUPPORTS WILL BE DEVELOPED THAT CAN SIGNIFICANTLY LOWER THE DOWNSTREAM PROCESSING COSTS OF BIOLOGICALLY SIGNIFICANT PRODUCTS SUCH AS ANTIBODIES, VACCINES, AND DRUGS. THE NEW SUPPORTS WILL BE SYNTHESIZED BY COATING THE COMPANY'S PROPRIETARY CALCIUM PHOSPHATE PARTICLES WITH THIN POLYMER LAYERS. THE COMBINATION OF POLYMER COATINGS WITH THE UNIQUE PARTICLE MORPHOLOGY ARE EXPECTED TO PROVIDE THE FOLLOWING ADVANTAGES SIMULTANEOUSLY: RIGIDITY, NON SWELLING, HIGH PRODUCTIVITY, HIGH PERFORMANCE, LINEAR SCALE-UP, LOW PRESSURE DROP, LOW NON-SPECIFIC ADSORPTION, BIOCOMPATIBILITY, AND LOW BLEEDING OF BONDED PHASES.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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