Development of a Real Time Crystallography Detector

Protein and virus crystallography imposes stringent requirements on detectors, particularly at highsynchrotron sources. This application describes a very advanced detector that can be used for both hsynchrotron x-ray-source protein crystallography and for dynamic laue diffraction studies. The detecReal-time Crystallography Detector (RCD). The RCD is a room-temperature, real-time, large-area, highresolution, high-speed, infinite-dynamic-range detector with a near-one Detective Quantum Efficiencyvery low diffraction peaks. The RCD is based upon advanced custom-designed Focal Plane Array (FPA) tis a very simple modular construction with no cooling requirements. It is a quantum-leap advance ovecrystallography detectors. The main focus of this study is to develop a detailed design of the RCD iwith our Stanford Synchrotron Radiation Laboratory (SSRL) collaborator and then to experimentally vecritical features of the design, the unit-cell area and electronic function of the unit-cell read-ouand one optional task will accomplish these goals. In Phase II the verified Phase I design parameterfabricate and test a full-scale detector. One of the Phase II test will be an x-ray crystallography