Collagen Based Ligament Template for ACL Reconstruction

The overall goal of this research is the design, development and in vivo testing of a type I collagtemplate to support the regeneration of the anterior cruciate ligament (ACL) of the knee joint. Thetemplate is biocompatible, bioresorbable and is fabricated from natural connective tissue componentswill define the procedure for extruding collagen filaments from highly purified bovine Achilles tenddevelop a prototype and test the prototype in vivo for healing response. During the past 20 years ofprosthesis the general conclusion has been that a permanent replacement of an ACL with a non-degradafulfill the function as a long term ACL substitute. The concept of ACL reconstruction using a resorbmade of extruded collagen filaments, to support the ligament regeneration has not yet been tested. Wdesigned collagen template has the potential to function as a temporary ligament substitute while suregenerate its own ligament.