SBIR/STTR Research Award

DETECTION OF OVULATON IN WOMEN

Award identifier 9fa39662f565cd3a0236e9cf09988dc9a1b21e08d54b016c6078b7fb7fffb8beAwarding agency Department of Health and Human Services

Award amount

$50,000

Program and phase

SBIR · Phase I

Award year

1989

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
Estrogenix Inc
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

THIS PROJECT WILL TEST THE EFFICACY OF A VAGINAL PROBE DESIGNED TO PREDICT THE ONSET OF OVULATION IN WOMEN. IT HASBEEN ESTABLISHED THAT PERIOVULATORY CERVICAL MUCUS VOLUME AND CONSTITUTION ARE DIRECTLY RELATED TO ESTROGEN LEVELS IN WOMEN. AS OVULATION NEARS AND FOLLICULAR ESTROGEN PRODUCTION INCREASES, THE CERVICAL MUCUS IN THE VAGINA UNDERGOES A NOTICEABLE SHIFT IN VISCOSITY AND ELECTRICAL CONDUCTIVITY. THE PROBE MEASURES THE ELECTRICAL RESISTANCE OF THE VAGINAL MUCUS AND THE SURROUNDING TISSUE. THE USER MAY THEN CHART THE CHANGE IN VAGINAL CONDUCTIVITY, THE NADIROF WHICH FORECASTS IMMINENT OVULATION. THE SYSTEM HAS ALREADY PROVEN USEFUL AND EFFECTIVE IN ANIMAL BREEDING PROGRAMS. IT IS THE INTENTION OF THIS STUDY TO DETERMINE THE FEASIBILITY OF USING THE SYSTEM IN WOMEN. NATURAL FAMILY PLANNING, TIMING OF ARTIFICIAL INSEMINATION, AND MANY OTHER FERTILITY CLINIC FUNCTIONS WOULD BENEFIT GREATLY FROM AN INEXPENSIVE, RELIABLE, AND EASY-TO-USE OVULATION DETECTOR. TWENTY SPONTANEOUSLY OVULATING WOMEN OF VARIOUS AGES WILL TEST THE PROBE AGAINST A BACKGROUND OF OTHER ACCEPTED (BUT MORE EXPENSIVE AND CUMBERSOME) OVULATION PREDICTION ASSAYS SUCH AS ULTRASOUND, BBT, AND LH ASSAYS.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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