SBIR/STTR Research Award

Novel Repeat Elements for Genome Analysis

Award identifier 4731675dde0925ce2884958259a00d8b1e6d083677d49d1eebb73b18914b4cb9Awarding agency Department of Health and Human Services

Award amount

$96,792

Program and phase

SBIR · Phase I

Award year

1995

Explore This Research Award in CaptureIQ

Research the technology, evaluate the recipient and agency, identify related opportunities, and explore potential follow-on work with CaptureIQ.

Open in CaptureIQRequest Access

Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
Genaissance Pharmaceuticals
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

The goal of this Phase I project is to isolate and characterize new chromosome-specific human repetelements. The resulting probes will be valuable for cytogenetic cancer diagnostics. Our preliminaryrandom amplification of polymorphic DNA (RAPD) is a valuable approach for the discovery of chromosompolymorphic repetitive DNA elements. Phase I will involve systematic and high- throughput employmentgenome-wide search for such elements. The repetitive DNAs will be cloned, then characterized by sequchromosomal localization and sublocalization, heterozygosity determination, evaluation of evolutionadetermination of average copy number. Additionally, Phase I will include modeling cytogenetic analyschromosomal aberrations using chromosome-specific repetitive DNA probes. Our model system will emplorepetitive element mapping to chromosome 20q12, which we discovered in preliminary research using RAprobe in interphase nuclei representing specific hematological malignancies known to have chromosomavicinity

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

Back to SBIR/STTR Research Awards

Don't take our word for it. Ask AI about RFPCapture.

See what leading AI assistants have to say about RFPCapture and CaptureIQ.

SmartSoloChatGPTClaudePerplexityGrokGemini

Gemini opens without a prefilled question. The question is copied to your clipboard when the button works. You can also copy it here:

What is RFPCapture.com and its CaptureIQ platform from Smart Logic AI? How does it help federal contractors discover opportunities, evaluate bid/no-bid decisions, research government contracts, and prepare proposals? How does it compare with other federal capture platforms? Use independent sources where available.