Piezoelectric Mass Loading for Bioidentification

Our ultimate goal is to develop small, inexpensive, disposable devices for rapid, on-site identificbiologically active molecules (hormones, metabolites, specific bacteria, etc.). The goal is based onloading onto a biosensitive material. An increase in mass on the surface of the biosensitive materiasignal received by an automatic reader. The investigators will design a screening system with two bireference one another. When a solution containing the test material is exposed to the sensors, theyloading of the specific material to different degrees. The degree of mass loading on the biosensorsautomatic reader. Phase I efforts will accomplish several tasks: 1) design a bioscreening system thavarious conditions; 2) develop techniques for binding bioactive materials; 3) critically quantitatethe surface of the material. This will require the use of radiolabeled materials so that the bindingdefined; 4) evaluate sensitivity of the bioscreening system using a model reaction. This will requiralgorithms to correlate the changes perceived by the automatic reader.