INTRA-ARTICULAR DELIVERY OF PEPTIDES AND PROTEINS

Not Available This project will investigate the feasibility of developing a compact, low-power, low-cost light probe to be used for remotely interrogating the fluorescence and reflectance properties of the sea floor and benthic marine organisms at a number of wavelengths. The resultant data would comprise the input to an automated bottom type classification algorithm. The point-by-point bottom classifications would in turn comprise the input to a statistical approach to characterization of the environment being surveyed. The system would be useable by divers or as a component on an autonomous or remotely operated underwater vehicle. The Phase I effort will include construction of a benchtop prototype of the primary sensor elements (light source and detectors), an experimental evaluation of the performance of the selected components, computer modeling of the implications of operating the sensor in the optically variable seawater environment, a computer evaluation of alternative schemes for processing and utilizing the sensor data stream, and a Phase II system design.