PRESCHOOL CONTINUOUS PERFORMANCE TASK

The CPT is the most sensitive measure available of sustained attention in preschool and school age children. Reaction time and number of errors differentiate normal groups of children from those with Attention Deficit Hyperactivity Disorder (ADHD). Recent studies of developmental aspects of sustained attention have shown that the CPT can be used effectively in 4- to 7-year old children. The Phase I research will yield a greatly improved, system independent, CPT software instrument to measure attention in 4- to 7-year old children. Phase II will produce a standardized, sophisticated CPT available for different platforms (Macintosh System 7.x; Motorola 68K/Power PCS; PC Intel MS NT). The use of highly sophisticated computer technologies within this simple to operate CPT instrument will: (1) empower much larger numbers of users in children hospitals, day care centers, preschools and/or children homes;; (2) enable better standardized measurement of attention in preschool children, and early diagnosis and treatment of ADHD; and (3) allow easy data sharing and analysis within the educational/medical/ scientific research community. This new valid CPT can be used for a wide variety of screening, diagnostic, prognostic, scientific and educational purposes. $ = TOTAL AWARD AMTS & NOT LIMITED TO PORTION OF PROJECT RELATED TO SUBJECT OF SEARCH SUBPROJECT $ = TOTAL AWARD AMOUNT DIVIDED BY NUMBER OF SUBPROJECTS SOURCE: CRISP FORMAT F FY 97 LAST UPDATE 04-07-98 1QUERY 1536 ID SEARCH 06/01/98 PAGE 370 --PROJECT NUMBER......2 R44 HD34330-02 INVESTIGATOR NAME/ADDRESS FY 97 COYLE, SALLYEANA IRG/INTRAMURAL UNIT..ZRG2 APPETEK INC AWARD AMOUNT......... $271,343 48 BIRNHAM LANE DURHAM, NC 27707-5174 PERFORMING ORGANIZATION: APPETEK, INC. TITLE DEVICE AND METHOD FOR AIDING DIET TRANSITIONS IN INFANTS ABSTRACT: Healthy infants often change diets. In addition many infants have a suspected allergy or metabolic abnormality that requires a transition to a therapeutic diet. Often these new diets are rejected by infants for a period of time. The effectiveness of our method and device will be tested with infants between the ages of 1 and 5 months. The infants sucking of normal and novel diet will first be determined. Then following 1 to 7 days of training with our device infants will again be tested to determine if sucking has been facilitated. A delayed test of up to 24 days will be used to examine the longevity of the effect. We will test healthy babies and those required to switch diets by a physician. The method and device derived from basic research on the biological psychology of learning were further developed by our company.