SBIR/STTR Research Award
An universal recipient for protein production in eggs
Award amount
$100,000Program and phase
SBIR · Phase IAward year
2001Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- ORIGEN THERAPEUTICS
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by applicant): To date, chimeric chickens are made by
injecting blastodermal cells or embryonic stem cells into the stage X embryo
(recipient), but the frequency and the level of chimerism is variable and
unpredictable. We plan to develop a universal recipient that contributes minimally,
so that the contribution of donor derived cells to the resulting chimera is constantly
high and predictable. Somatic chimeras can be used to produce biopharmaceutical
proteins in eggs as soon as the chimeras commence laying and before they transmit
the gene encoding the biopharmaceutical protein to the next generation.
PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE
Technology keywords
Not reported