Investigator Ready, Interconnected Microprobe Systems

We will develop completed, implantable systems utilizing microelectrode probes, lead wires and percconnectors to record neural activity inside the body. High failure rates of current microprobe systill-suited interconnect systems and inadequate termination, cleaning and encapsulating processes anddevelopment effort would capitalize on existing photolithographically micromachined silicon microelecombination with implantable micro-ribbon cable and system interconnect technology developed by PI Mstandardized, investigator-ready microprobe systems suitable for a wide range of emerging diagnosticmedical devices. In Phase I, we will work closely with research groups to standardize interface geomfabricate several microelectrode system prototypes. Comprehensive electrical and mechanical characteconducted prior to applications. These results will provide the additional impetus to develop full smethods and biocompatibility studies in a Phase II program for the commercialization of these enablitechniques and methods developed in this proposal will facilitate commercialization of micromachinedextending their application into commercial diagnostic and therapeutic medical devices.