SBIR/STTR Research Award
Identifying Novel Inhibitors of Viral Translation
Award amount
$749,999Program and phase
SBIR · Phase IIAward year
1996Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- RIBOGENE, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
Human rhinoviruses, coxsackieviruses, hepatitis A viruses, and hepatitis C viruses are commerciallyhave established an in vitro screening system to identify compounds that inhibit translation of viruPhase I funding will be used to establish screening systems for coxsackievirus, hepatitis A virus, aanalogous to a rhinovirus screening system already established. Mass screening of natural product exchemical entities for agents that inhibit translation of these viruses will also begin in Phase I. Hcoxsackievirus, hepatitis A virus, and hepatitis C virus translation systems are excellent targets fsince they are essential for viral replication and function very differently than the translation syhuman mRNAs.
Technology keywords
Not reported