SBIR/STTR Research Award
An Efficient Fully 3-Dimensional Cell Migration Assay
Award amount
$147,446Program and phase
SBIR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- PLATYPUS TECHNOLOGIES LLC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- CR97YQK8M1U5
- Solicitation number
- PA13-234
- Topic code
- NIGMS
Research abstract
DESCRIPTION (provided by applicant): The goal of this SBIR project is to design and develop an efficient, physiologically relevant and cost-effective 96-well 3-D Cell Migration Assay that is compatible with mid-high throughput/high content assay platforms.Due to its importance in cancer and associated metastatic processes, cell migration is intensively studied and in vitro cell migration assays are routinely used in drug discovery programs aimed at identifying new cancer therapeutics. Cell migration studies of cells grown in 3-D biomimetic matrices are currently performed primarily using trans-membrane well inserts and microfluidic systems. These methods are expensive, laborious and provide inconsistent data. Moreover, these assays compromise on an important characteristic of the in vivo environment: the unique spatial arrangement of cells that facilitates their ability to exhibit normal physiological phenotypes and functions. A major barrier to efficient screening of candidate cancer therapeutics affe
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Wearable Multi-Gas Technologies for Monitoring Personal Air Quality
- A direct-reading dosimeter badge for monitoring personal exposure to Polycyclic Aromatic Hydrocarbons (PAHs)
- A Direct-Reading Liquid Crystal Based Formaldehyde Dosimeter for Personal Exposure Monitoring
- Wearable Liquid Crystal Based Chemical Sensor Badge for the Identification of Toxic Industrial Chemicals
- Liquid Crystal-based Sensors for Detection of Airborne Toxic Chemicals for Integration with Unmanned Robotic Systems
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Three-Dimensional Spatio-Temporal Control of Lipid Nanoparticle Manufacturing for Improved Nucleic Acid Delivery
- Paradigm-changing, versatile, scalable and cost-effective technology for monthly injections of peptide drugs
- Project MATCH: Multi-spectral AI/ML powered Burn and Wound Evaluation Technology using a Cost-Effective Handheld Device.
- A versatile platform to isolate cells from three-dimensional samples after spatial and temporal profiling
- Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States
Research funding history
34 SBIR/STTR records share this UEI (2001–2022). Reported award amounts total $16,425,324. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services, Department of Defense, National Science Foundation, Department of Homeland Security, Department of Agriculture