SBIR/STTR Research Award
LIPOSOME-ENCAPSULATED B-10 FOR NEUTRON CAPTURE THERAPY
Award amount
$50,000Program and phase
SBIR · Phase IAward year
1987Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Vestar, Inc.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
NEUTRON CAPTURE THERAPY IS AN ATTRACTIVE ALTERNATIVE TO STANDARD RADIATION TECHNIQUES FOR CANCER TREATMENT IF NUCLEI, SUCH AS (10)B, CAN BE SELECTIVELY CONCENTRATED IN TUMORS. SMALL, UNILAMELLAR, PHOSPHOLIPID VESICLES ARE KNOWN TO BE TAKEN UP BY ANIMAL AND HUMAN TUMORS. LIPOSOME FORMULATIONS WILL BE TESTED FOR THEIR ABILITY TO ENCAPSULATEHIGH CONCENTRATIONS OF BORON COMPOUNDS IN A STABLE MANNER. BIODISTRIBUTION OF THESE B-CONTAINING LIPOSOMES WILL BE TESTED IN MICE BEARING EMT6 TUMORS WITH RADIOLABELED NA2B10H10.
Technology keywords
Not reported