SBIR/STTR Research Award

Cavernosal Nerve Repair Following Radical Prostatectomy

Award identifier bf5aeceb36162ee89e5afd717b6d006ed4e3dd22b646f3fd6e5c7df10f146677Awarding agency Department of Health and Human Services

Award amount

$99,990

Program and phase

SBIR · Phase I

Award year

1995

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
INTEGRA LIFESCIENCES CORPORATION
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

Impotency caused by cavernosal nerve injury is a devastating complication of radical prostatectomy.restoring erectile function following cavernosal nerve section in animal models, cavernosal nerve readopted clinically, due to 1) perceived and practical difficulties, 2) reluctance to destroy healthyprovide autograft material, and 3) secondary operations required to remove nonbioresorbable prosthesalternatives to standard clinical nerve repair methods, it is unlikely that sectioned cavernosal nerradical prostatectomy. The successful application of the collagen-based nerve guide to cavernosal nedevelopment of an entirely novel clinical procedure. Bioresorbable collagen-based nerve guide repairdeficits will be examined in 60 rats. Bilateral section and repair by either nerve guide tube or ner2 and 4 months in each animal by behavioral studies, providing categorical "all or nothing" assessmerecovery. They are crucial, as successfully restorating sexual potency is the fundamental purpose ofII. Physiological tumescence studies, demonstrating the continuum of functional recovery following rHistological analysis, quantifying axon regeneration through the repair sites and maturation of remy

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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