SBIR/STTR Research Award
Computer-based HIV Prevention for Seropositive Men
Award amount
$1,085,974Program and phase
SBIR · Phase IIAward year
2013Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- ISA ASSOCIATES INC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- NJM4F3D4PR44
- Solicitation number
- PA12-088
- Topic code
- NIMH
Research abstract
DESCRIPTION (provided by applicant): Sexual transmission is the predominant route of HIV infection in the United States, and it is men who are primarily spreading the virus. Male-to-male sexual contact accounts for 72% of all new HIV infections in men while heterosexual contact accounts for 83% of all new HIV infections in women. Extrapolating this incidence data reveals that 75% of all new HIV cases result from high risk sexual activity by men. These new infections are also not evenly distributed throughout the population. African Americans comprise only 14% of the US population, but account for 44% of the new infections. Black men, in particular, are disproportionately burdened, accounting for 70% of new HIV cases among African Americans. In addition, African Americans tend to have sex with people of the same race. As the prevalence of HIV increases within this community, the risk of infection concomitantly increases with each new sexual encounter. Given this epidemiological reality, reducing sexual risk behaviors among African American HIV+ men who have sex with men (MSM), with women (MSW), and with both men and women (MSM/W) is a prevention imperative. To address this, we intend to develop and test Positively tHrIVing, an HIV behavioral intervention basedon modules 2 and 3 of the Healthy Living Project (HLP; a best evidence CDC intervention), and then tailored it to fit the unique needs of HIV+ African American men (both MSM and MSW). This will include a focus on the distinctive challenges faced by all men independent of race (e.g., the influence of gender roles on sexual risk behaviors), faced by African-Americans living in the United States (e.g., discrimination, socioeconomic issues), and the intersection of these factors with the gender of sexual partners (e.g., managing power inequalities in heterosexual relationships v. facing homophobia and cultural issues). Additionally, Positively tHrIVing will adopt a pro-health point of view so that it will be perceived as supportive and nonstigmatizing. Finally, Positively tHrIVing will be computer-based to further increase acceptability among patients and physicians, reduce staff time, lower costs, increase fidelity of treatment delivery, and enhance the probability of widespread dissemination. The results ofPhase I strongly support the feasibility and potential effectiveness of the program - far exceeding the three usability benchmarks established in the Phase I proposal. In Phase II we will complete development of the Positively tHrIVing program and test itseffectiveness in a pretest-posttest experimental design. 240 HIV+ African American men will be randomly assigned to receive either the computer-based Positively tHrIVing program or flash-enabled STD CDC fact sheets. Before, and at two points after randomassignment, participants' sexual transmission risk behavior, medication adherence, disclosure, health behaviors, and substance use will be assessed through an online survey-questionnaire. PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: This project aims to develop a computer-based HIV behavioral intervention for HIV+ African American men. For clinics, this will allow them to provide an empirically validated HIV prevention intervention to their clients without creating additional demands on theiralready overburdened staff. For HIV+ African American men, the skills contained in this program will help them reduce risk behaviors and, ultimately, prevent the spread of HIV.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- A Mobile Intervention to Reduce the Impact of Chronic Stress on Preterm Birth Risk in African American Women
- Quédate Tranquila: A Mobile, Web-based Stress Management Intervention for Hispanic Women
- An mHealth Approach to Decreasing Opioid Abuse and Other Diseases of Despair in Rural Populations
- Reducing Hypertension among African American Men: A Mobile Stress Management Intervention to Address Health Disparities
- Enhancing the Effectiveness of Community Health Workers to Reduce Cervical Cancer Disparities in African American Women
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
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- The Development and Systematic Evaluation of an AI-Assisted Just-in-Time-Adaptive-Intervention for Improving Child Mental Health
- Scalable, non-dissociative single-cell RNA sequencing for mapping the brain in health and disease
- A MEMS-Based High-Throughput Photostimulation Device with Commercial Backplane Integration