SBIR/STTR Research Award

Lipophilic Calcium Fluoroionophores

Award identifier b673be3985c0485a7bbc25eb63d31c8cfcc84096c62b66e6d906b67482b32d67Awarding agency Department of Health and Human Services

Award amount

$74,999

Program and phase

SBIR · Phase I

Award year

1994

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
COVALENT ASSOC., INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

We will synthesize and test new lipophilic fluorescent ionophores for measuring calcium ionconcentrations in aqueous solutions. The ionophores are designed to be soluble in synthetic membranesand to respond selectively to Ca2+ in a contacting aqueous solution by undergoing a shift in absorptionand emission to longer wavelengths. Theses compounds will be of primary interest for incorporating intoa fiber optic chemical sensor (FOCS). A FOCS device will be of use for determining the concentrationof calcium ion in biological fluids in vitro and ultimately in vivo. A device based on this design wouldbe valuable in the intensive care unit or other hospital facility.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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