SBIR/STTR Research Award

RESEARCHERS WILL DESCRIBE STUDIES DESIGNED TO DEVELOP SPECIFIC DIAGNOSTIC ASSAYS OF ATRIAL NATRIURETIC FACTOR AND ITS METABOLITES.

Award identifier 6fab66babfa27978df9a553892399a093e089823cecd32234aab5135c321712fAwarding agency Department of Health and Human Services

Award amount

$50,000

Program and phase

SBIR · Phase I

Award year

1986

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
California Biotechnology, Inc.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

RESEARCHERS WILL DESCRIBE STUDIES DESIGNED TO DEVELOP SPECIFIC DIAGNOSTIC ASSAYS OF ATRIAL NATRIURETIC FACTOR AND ITS METABOLITES. SUCH ASSAYS ARE CURRENTLY NOT AVAILABLE BUT ARE REQUIRED FOR A COMPLETE UNDERSTANDING OF ATRIAL NATRIURETIC FACTOR IN THE REGULATION OF BLOOD PRESSURE. THIS STUDY INVOLVES THE PREPARATION AND USE OF MONOCLONAL ANTIBODIES TO DEFINED REGIONS OF THE PEPTIDE. THE RADIO ANDFLOURIMETRIC ASSAYS DEVELOPED CAN BE UTILIZED TO STUDY THE EXCRETION, FATE, AND METABOLISM OF ANF AND TO SERVE AS DIAGNOSTIC TOOLS TO EXPLORE LIKELY CORRELATIONS BETWEEN CHARACTERISTIC ANF LEVELS AND CERTAIN CARDIOVASCULAR DISORDERS.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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