SBIR/STTR Research Award
Identification and Quantification of Sequence Specific RNA Modifications via the Alpha-Hemolysin Latch Zone
Award amount
$215,741Program and phase
STTR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- ELECTRONIC BIOSCIENCES, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- FLHHE89XH2H5
- Solicitation number
- DA15-002
- Topic code
- NIDA
Research abstract
DESCRIPTION (provided by applicant): During this STTR program, Electronic BioSciences (EBS) proposes to develop a nanopore based system around our University of Utah collaborators newly developed technology that will be capable of identifying and quantifying sequence specific RNA modifications. A system capable of quantitative, low cost, high throughput, RNA modification characterization has the capability to elucidate the roles of these modifications in cellular signaling, and improve our understanding ofgene regulation and associated disease states. The goal of this Phase I program is to demonstrate proof-of-concept for the RNA modification characterization concept, and determine the parameters that will allow our team to develop a complete RNA modification characterization system during a follow-on Phase II program. PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: This program is aimed at developing a new method and system for the characterization of sequence specific RNA modifications. This system will
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Rapid Fingerstick Diagnostics for Opioid and Stimulant Use Disorders
- Direct Proteolytic Machine Assessments for Unfolding and Sequencing Proteins
- High-Resolution Pseudouridine and m6A Sequencing Through Advanced Nanopore Adduct Analysis
- Fourth-Generation Nanopore-Assisted Sequencing for Advanced Oncological Analyses
- Re-Reading RNA to Obtain High Accuracy
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression
- Building and testing the Life Enhancement and Advocacy Programming digital training tool (LEAPLink) to better serve people with lived experience of homelessness and substance use disorder
- A digital intervention to decrease self-stigma among pregnant and postpartum women with opioid use disorder
- Development of medication for the treatment of respiratory depression due to opioid (prescribed or illicit) overdose/multidrug (polysubstance) overdose in a hospital or community setting.
- Creation and Validation of the Dose-Opioid-Source Evaluation tool (DOSE) - a Robust Opioid Use Clinical Outcome Assessment for Qualification as an FDA Medical Device Development Tool (MDDT)
Research funding history
58 SBIR/STTR records share this UEI (2007–2025). Reported award amounts total $22,847,588. Reported amounts are not federal obligations.
Phases: Phase I, Phase II, Phase II – Direct to Phase II
Agencies: Department of Health and Human Services, National Science Foundation, Environmental Protection Agency, Department of Defense, Department of Commerce