Data System for High Speed Chromatography

We will develop a high speed data system which uses a time-of-flight mass spectrometer (TOF-MS) asmass separation device and species detector. This data system will take advantage of the temporal spmass spectrometry to rapidly compute and display either liquid chromatography (LC) or capillary elecusing both Electrospray and Atmospheric Pressure Chemical Ionization (APCI) as inlet systems. 'Standand presentation will be performed, including ion chromatograms and both raw and averaged mass spectvirtue of the statistically significant numbers of spectra which one can generate using TOF-MS as adetector, other multi-parametric relationships will also be computed and presented. The data systemfour individual elements: a data acquisition module, a data storage module, high speed data reductiodata presentation module. A prototype data system including all of the above modules will be designetested in Phase I. This system will possess rudimentary real-time computational abilities which willPhase II studies.