SBIR/STTR Research Award

Organophosphate intoxication: effect of PARS inhibition

Award identifier 8894c629333a9270427192255183a2348b6dd8e6fb80dbc3a201498ee2e0fb7eAwarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$240,309

Program and phase

SBIR · Phase I

Award year

2004

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
Inotek Pharmaceuticals Corporation
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
PHS2004-2
Topic code
Not reported

Research abstract

DESCRIPTION (provided by applicant): Activation of poly (ADP)ribose synthetase (PARS) (also known as poly(ADP)ribose polymerase or PARP) is a novel mechanism of oxidant-induced neuroinjury. Triggered by DNA single strand breakage, PARS catalyzes an en

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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