SBIR/STTR Research Award
SBIR PHASE 1 (NIH/NIMH TOPIC 002 - DEVELOPMENT OF NOVEL IN-VITRO AND IN-VIVO MODELS TO SUPPORT NEUROHIV RESEARCH)
Award amount
$300,000Program and phase
SBIR · Phase IAward year
2024Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- VALA SCIENCES, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- CZZJVX2BKJF3
- Solicitation number
- PHS-2024-1
- Topic code
- 2
Research abstract
This Phase I SBIR contract is in support of Development of novel In-vitro and In-vivo Models to support NeuroHIV Research. hiPSC-NeuroHIV assay, an in vitro model system that mimics certain cellular components of the human brain using cells derived from human induced pluripotent stem cells (hiPSCneurons/ microglia/astrocytes). The hiPSC-NeuroHIV assay system will enable HIV-therapeutics and cART mixtures to be tested for both NeuroHIV effects (neurotoxicity), and for efficacy at blocking HIV replication. has context menu
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- An assay suite featuring hiPSC-derived neurons and support cells, to test toxicants and industrial chemicals for developmental neurotoxic effects
- Neural Circuits, Kinetics and Energetics HTS of Human iPSC-Neurons, -Microglia, and -Astrocytes: AI-Enabled Platform for Target ID, and Drug Discovery and Toxicity (e.g., Cancer Chemo & HIV ARTs)
- Neural Circuits, Kinetics and Energetics HTS of Human iPSC-Neurons, -Microglia, and -Astrocytes: AI-Enabled Platform for Target ID, and Drug Discovery and Toxicity (e.g., Cancer Chemo and HIV ARTs)
- Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes
- The Pain in a Dish Assay (PIDA): a high throughput system featuring human stem cell-derived nociceptors and dorsal horn neurons to test compounds for analgesic activity
Research funding history
37 SBIR/STTR records share this UEI (2006–2024). Reported award amounts total $27,661,877. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services