SBIR/STTR Research Award
Vaccine Approaches to Treatment of Hepatitis C Infection
Award amount
$749,544Program and phase
SBIR · Phase IIAward year
1998Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Cytel Corp.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
The overall aim of our studies is to derive a potential HCV vaccine, based on the induction of HCV-To do so, we will identify a synthetic formulation composed of at least two A2-restricted CTL epitopconserved regions of the HCV genome. Such formulation will also contain universal T helper epitopesdemonstrated to be efficacious in inducing specific A2-restricted CTL responses in vivo, utilizing Hmice. In parallel studies additional potential epitopes specific for several of the major HLA types
Technology keywords
Not reported