SBIR/STTR Research Award
ANIMAL MODEL OF ETHANOL-INDUCED CARDIOMYOPATHY
Award amount
$279,270Program and phase
SBIR · Phase IAward year
2002Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- GWATHMEY, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by applicant): This proposal was prepared in response to
the National Institute on Alcohol Abuse and Alcoholism request for proposals to
develop new models that more closely mimic human disease. Studies on the
effects of ethanol on myocardial contractility have been ongoing for over the
last twenty years. Studies in animals chronically administered ethanol and
models of ethanol-induced disease studied previously, as well as currently, do
not compare well to the human condition. Reproducible ethanol-induced
cardiomyopathy has been difficult to produce in animals. This has hindered
experimental studies of this disease. No one to date has produced congestive
cardiomyopathy or heart failure in an animal model of chronic ethanol intake.
Technology keywords
Not reported