SBIR/STTR Research Award
IN ORDER TO FACILITATE THE ULTIMATE PRODUCTION OF A DIAGNOSTIC AND VACCINE FOR HUMAN VIRAL NANB HEPATITIS USING RECOMBINANT DNA TECHNOLOGY, STRATEGIES DESIGNED TO ISOLATE VIRAL NUCLEIC ACID WILL BE INITIATED THROUGH THE PRODUCTION OF ENRICHED RECOMBINANT
Award amount
$50,000Program and phase
SBIR · Phase IAward year
1985Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Chiron Corp
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
IN ORDER TO FACILITATE THE ULTIMATE PRODUCTION OF A DIAGNOSTIC AND VACCINE FOR HUMAN VIRAL NANB HEPATITIS USING RECOMBINANT DNA TECHNOLOGY, STRATEGIES DESIGNED TO ISOLATE VIRAL NUCLEIC ACID WILL BE INITIATED THROUGH THE PRODUCTION OF ENRICHED RECOMBINANT CDNA LIBRARIES AND BY DIRECT RADIO-LABELING STUDIES. IN ADDITION, MONOCLONAL ANTIBODIES WILL BE MADE AGAINST VIRUS PREPARATIONS AND AN IN VITRO SYSTEM FOR PROPAGATING VIRUS INVESTIGATED. AN ASSOCIATION OF REVERSE TRANSCRIPTASE ACTIVITY WITH VIRUS WILL ALSO BE INVESTIGATED. PROGRESS IN THESE AREAS SHOULD LEAD TO THE MOLECULAR CLONING, CHARACTERIZATION, AND RECOMBINANT EXPRESSION OF THE VIRUS GENOME WHICH IN TURN WILL ALLOW DIAGNOSTIC DEVELOPMENT AND
Technology keywords
Not reported