SBIR/STTR Research Award
URINARY TRACT INFECTIONS ASSOCIATED WITH URINARY DRAINAGE CATHETERS ARE A SIGNIFICANT CLINICAL PROBLEM RESULTING IN A PROLONGED HOSPITAL STAY AND AN INCREASED MORTALITY RISK.
Award amount
$50,000Program and phase
SBIR · Phase IAward year
1985Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Biomaterials International Inc
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
URINARY TRACT INFECTIONS ASSOCIATED WITH URINARY DRAINAGE CATHETERS ARE A SIGNIFICANT CLINICAL PROBLEM RESULTING IN A PROLONGED HOSPITAL STAY AND AN INCREASED MORTALITY RISK. THIS PROPOSAL ADDRESSES A FEASIBILITY STUDY TO DETERMINE IF SURFACE MODIFICATION OF THE CATHETER WILL INHIBIT BACTERIAL MIGRATION. THE PROPOSED RESEARCH WILL TEST THE HYPOTHESIS THAT BACTERIAL FIVE DIFFERENT SURFACE TREATMENTS WILL BE APPLIED TO SILICONE RUBBER URINARY CATHETERS TO MINIMIZE BACTERIAL ADHESION. THE CATHETERS WILL BE CHARACTERIZED BY MICROSCOPY, ESCA, AND CONTACT ANGLE ANALYSIS. IN VITRO BACTERIAL MIGRATION WILL BE DETERMINED USING A MIGRATION MODEL DEVELOPED FOR BIOMATERIALS INTERNATIONAL. STABILITY OF THE SURFACE TREATMENTS WILL ALSO BE EVALUATED
Technology keywords
Not reported