SBIR/STTR Research Award
IGF OT IGF BLOOD TEST TO PREDICT RADIATION TOXICITY IN PATIENTS TREATED WITH RADIATION THERAPY
Award amount
$1,498,643Program and phase
SBIR · Phase IIAward year
2016Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- DXTERITY DIAGNOSTICS INCORPORATED
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- L2MYPKV2PNG3
- Solicitation number
- Not reported
- Topic code
- NCI
Research abstract
In this Phase II project the goal is to continue development and validate the radiation toxicity RadTox diagnostic test We will also explore if gene expression in blood can be used to predict radiation sensitivity In our Phase I study gene expression based biomarkers were identified the DxDirect based assay was developed and the prototype predictor algorithm was developed In Phase II the sample size will be increased to at least patients confounders will be identified the gene expression assay will be further developed and validated and the locked assay will be transferred to DxTerity s CLIA CAP laboratory for initial commercialization We will also begin Quality System Regulation QSR compliant product development During this Phase II SBIR contract we will complete Phase and Phase of product development DxTerity s long term intention is to submit the assay for eventual FDA clearance with the intention of being a product line upgrade to DxTerity s REDI Dx High Throughput Biodosimetry assay
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- SBIR TOPIC 315: DEVELOPMENT OF COMPANION DIAGNOSTICS: ENABLING PRECISION MEDICINE
- One-Step In Situ RNA Integrity Analysis for FFPE Tissue
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment
- Development of small molecule therapeutics targeting AR-V7 for prostate cancer
- Decentralized Clinical Trial of Effectiveness of EnergyPoints App to Guide Acupressure Use for Fatigue and Sleep Disturbances in Cancer Survivors
- Optimized targeted radiotherapy of pancreatic cancer
- Adaptive imaging for pioneering multiplexed spatial profiling of tumors and tissues for cancer research and diagnosis
Research funding history
3 SBIR/STTR records share this UEI (2011–2016). Reported award amounts total $1,945,603. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services