TOPIC 383: MULTI-CORE BIOPSY DEVICE WITH VOLUMETRIC FIELD OF TISSUE ACQUISITION (MOONSHOT)

The problemTumor recurrence or resistance to treatment often arises due to tumor heterogeneityThere is a need to develop smart biopsy devicesto collect biopsies from multiple tumor coresto identify locations of the biopsiesto maintain physical characteristics of tumor on the extracted samplesto be used under current image guided practicesWe propose to further develop a prototype of multi core biopsy deviceMCBDthat we have already developed to enable collection of multi core tissue samples in a volume around the biopsy needleWe expect to provide prototype device that will enable rapid acquisition and preservation of multiple tissue cores under electromagnetic position navigationIf successfulthe project will have substantial commercial potential as the proposed device will facilitate the acquisition of multiple tissue cores in any tissue type and with any needle size and will improve the quality of biomolecular analysis by better preservation and handling of the tissue samplesThis research has substantial effect on public health as it can reduce healthcare cost by shortening image guided biopsy proceduresand it can improve patient management by better matching between tumor type and specific therapy based comprehensive evaluation of the tumor and better tissue preservation