Non-invasive Device for Diagnosis of Compartment Syndrome

Spectra Research, Inc. (S*R) proposes to leverage its current development efforts to investigate a novel method for identifying compartment syndrome in medical trauma cases. The proposed method is based on S*R's Non-Invasive Field Triage Device (NFTD) thatuses electromagnetic waves in the X-band frequency range and special signal processing algorithms to detect the presence of various internal injuries. In the proposed Phase I program, S*R will employ its patented RF interrogator and software algorithms tothe clinical condition of compartment syndrome. Compartment syndrome is defined as the clinical condition in which high pressure within a closed fascial space (muscle compartment) reduces capillary blood perfusion below the level necessary for tissueviability. In previous studies, the S*R technology has been able to detect changes in the dielectric signature from various medium including fluid accumulation in the cranium, collapse lung (pneumothorax), and hemorrhagic stroke. Independent third-partystudies have also suggested that this technology can detect as little as 2cc or greater of fluid in an injured limb. Spectra Research, Inc. (S*R) is developing an ambitious plan to take the NFTD technology from the laboratory to the military and civilianfirst responder markets. This plan has been presented to various Federal, state, and local agenices, including the U.S. Army; and the interest in such a device is quite high. S*R recognizes that development of the NFTD will require expertise in the designand packaging of medical equipment, as well as knowledge of the relevant radio frequency (RF) parameters associated with the system. S*R plans to retain the services of medical instrumentation personnel, phycisians, and other experts as a consultant base.Initial discussions have also begun with major RF equipment manufacturers for assistance in the development of the NFTD. Prior efforts have produced initial market estimates that indicate a significant opportunity exists.