SBIR/STTR Research Award

LIQUID-GUIDED ACOUSTIC WAVE IMMUNOSENSOR

Award identifier dda702287c4f5c0312b3ff52ed634bae95a516ee414ea778fb66ac553e7e7efaAwarding agency Department of Health and Human Services

Award amount

$50,000

Program and phase

SBIR · Phase I

Award year

1989

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
BIODE, INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

BIODE, INC., WILL UTILIZE THE RESULTS OF ITS PHASE I RESEARCH TO DEVELOP A TOTALLY NEW SOLID-STATE BIOSENSOR TECHNOLOGY FOR BIOLOGICAL MEASUREMENTS. THIS TECHNOLOGY IS BASED UPON THE MERGING OF TWO OTHER RELATIVELY NEW TECHNOLOGIES, MONOCLONAL ANTIBODIES (HYBRIDOMA TECHNOLOGY) WITH ACOUSTIC WAVE MICROSENSORS. BY COMBINING THE SENSITIVITY OF ACOUSTIC WAVE SENSORS WITH THE SPECIFICITY OFANTIBODIES, BIODE, INC., WILL CREATE A NOVEL DETECTION TECHNOLOGY WITH THE POTENTIAL TO OVERCOME THE DRAWBACKS OF EXISTING IMMUNOASSAY TECHNOLOGY. THIS NEW IMMUNOSENSOR WILLOPERATE IN A CONTINUOUS AND THEREFORE HOMOGENEOUS MODE, YET IT IS EXPECTED TO EQUAL OR EXCEED THE SENSITIVITY LIMITS OF EXISTING HETEROGENEOUS IMMUNOASSAYS. AN ACOUSTIC WAVE MICROSENSOR BASED UPON THE PRINCIPLE OF LIQUID-GUIDED ACOUSTIC WAVE (LGAW) TECHNOLOGY WILL BE TESTED. THE IMMUNOSENSOR TECHNOLOGY WILL ALLOW FOR HOMOGENEOUS ASSAYS THAT MEET OR EXCEED THE PRESENT STATE-OF-THE-ART HETEROGENEOUS ASSAYS. AS THE LGAW IMMUNOSENSOR TECHNOLOGY PROPOSED BY BIODE, INC., DOES NOT NOW EXIST, IT REPRESENTS A TRUE TECHNOLOGICAL INNOVATION SHOULD THE FEASIBILITY RESULTS OF PHASE I RESEARCH PROVE FRUITFUL.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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