SBIR/STTR Research Award
HIGHLY EFFICIENT ISOLATION AND FIDELITY DIFFERENTIATION OF EXOSOMES HIFIDE FROM BODILY FLUIDS KIT
Award amount
$299,980Program and phase
SBIR · Phase IAward year
2017Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- CHROMOLOGIC LLC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- D9EVNTKKWLF3
- Solicitation number
- Not reported
- Topic code
- NCI
Research abstract
Exosomes encapsulate and transport a wide variety of molecules generated by their cell of origin a process now thought to be a form of cellular signaling Exosome signaling is common across cell types and species but it is of particular interest in diseases with an inflammatory component While exosome isolation and analysis is useful to understanding the mechanisms behind these multifaceted diseases exosomes may also be exploited for their therapeutic potential In particular exosomes derived from healthy cells have been found to effectively alter the transcriptome of cancer cells Nonetheless there are no methods for differentiating between healthy and cancer cell derived exosomes in bodily fluids In this project we aim to develop a method for isolating exosomes and oncosomes coupled with a method for the differentiation of exosome populations
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Mitigation of Ionizing Irradiation-Induced Intestinal Damage by Second-Generation Probiotic LR-IFN-β
- Membrane-based AWE Device (MAWED)
- Ceramic membrane based portable oxygen generator (CEMPOG)
- CRISPR-based Assay for Portable Tropical Infection Diagnosis (CAPTIN-D)
- Wearable Heat Related Injury Risk Analysis (WHERA) system Resubmission
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment
- Development of small molecule therapeutics targeting AR-V7 for prostate cancer
- Decentralized Clinical Trial of Effectiveness of EnergyPoints App to Guide Acupressure Use for Fatigue and Sleep Disturbances in Cancer Survivors
- Optimized targeted radiotherapy of pancreatic cancer
- Adaptive imaging for pioneering multiplexed spatial profiling of tumors and tissues for cancer research and diagnosis
Research funding history
93 SBIR/STTR records share this UEI (2007–2025). Reported award amounts total $49,103,552. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Defense, Department of Health and Human Services, National Aeronautics and Space Administration, Department of Energy