Mechanistically-based Biosensors for Toxicity Test Kit

There is a need to develop rapid, inexpensive, accurate mechanistically-based toxicity test kits for the assessment of new chemicals being developed for various applications. Currently, no such technology is available. This effort aims at developing biosensors that can enable such test kits. Phase I will establish the proof-of-concept. Phase II will optimize and produce prototype test kit. Phase III will commercialize the technology. BENEFITS: The toxicity test kits will be useful in rapid and early assessment of carcinogenic, developmental, immunotoxicologic, neurotoxicologic, and reproductive toxic contaminants in single exposure situations or in complex environmental contamination. The kit will also be an enabling non-invasive hazard and environmental monitor.