Development of Web-driven Bioinformatic Platform for Microarrays

"The objective of this proposal is to create an innovative bioinformatics system for the management and analysis of microarray data. It will be a new generation of informatics system that goes well beyond any system presently available. The system will notonly allow users to track the generation of data with a flexible laboratory information management system (LIMS), but it will also allow users to track and manage the analysis of the data automatically with a pioneering analysis information managementsystem (AIMS). The AIMS portion of the system interfaces with external bioinformatics tools and databases to allow users to process and interpret their data. The integration of LIMS and AIMS will produce dramatic new benefits to researchers in terms ofimproved research quality and decreased time to biological discovery. Existing microarray informatics systems are very incomplete solutions because they fail to address the entire process and fail to track and integrate critical experimental and analysisinformation. No existing solution provides as complete or as integrated a solution as system proposed here. Technologies developed for this proposal will also be extremely effective for the management and analysis of other biological, high throughputfunctional data besides microarrays. Benefits: Significant cost reductions for conducting and analyzing microarray experiments. Dramatic improvements in the speed for conducting microarray experi