SBIR/STTR Research Award
THIS STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF REPLACING A HOLLOW VISCUS WITH A PROSTHESIS THAT ALLOWS PRIMARY MUCOSAL HEALING AND INCORPORATION OF THE PROSTHETIC INTO THE HEALING PROCESS.
Award amount
$47,000Program and phase
SBIR · Phase IAward year
1986Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Deseret Research Company Inc
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
THIS STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF REPLACING A HOLLOW VISCUS WITH A PROSTHESIS THAT ALLOWS PRIMARY MUCOSAL HEALING AND INCORPORATION OF THE PROSTHETIC INTO THE HEALING PROCESS. HEALING OF A FULL THICKNESS ISOLATED BOWEL SEGMENT TO 2 TYPES OF A HOLLOW VISCUS PROSTHESIS WILL BE EVALUATED IN DOGS. BOTH TYPES OF PROSTHESIS WILL CONSIST OF AN OUTER RIGID MESH AND A BIO- DEGRADABLE MIDDLE LAYER. THE TYPE A PROSTHESIS WILL HAVE ANINNER IMPERVIOUS LAYER, THE TYPE B PROSTHESIS WILL NOT. THEPROSTHESES WILL BE EVALUATED AT VARIOUS POSTIMPLANTATION TIMES OF UP TO AND INCLUDING 60 DAYS. EVALUATION OF HEALINGPATTERNS OF THE PROSTHESES AND MUCOSAL REGENERATION, INFECTION, CONNECTIVE TISSUE INGROWTH, REJECTION, AND STRICTURE WILL BE PERFORMED BY GROSS EXAM AND LIGHT MICROSCOPY.
Technology keywords
Not reported