SBIR/STTR Research Award
DNA Vaccines for Anthrax: Targeting Afferent Immunity
Award amount
$148,163Program and phase
SBIR · Phase IAward year
2003Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- Genitrix, LLC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by the applicant): B. anthracis is a pathogen of major concern for national biodefense. DNA vaccines have a number of potential advantages in this context. However, they often elicit only modest immune responses. We will generate candidate DNA vaccines for anthrax that incorporate a proprietary technology which targets the afferent limb of the immune system, markedly amplifying the immune response. The technology may also accelerate the response. We will test our vaccines in non-infectious mouse models.
Technology keywords
Not reported