CLOUD HOSTED CLINICAL TRIAL IMAGING ASSESSMENT AND WORKFLOW MANAGEMENT SYSTEM

Over the past two decades clinical trials have become increasingly dependent upon image based surrogate endpoints for evaluation of cancer therapeutics The growing complexity of image based response evaluation criteria has made it challenging for radiologists to provide reliable timely protocol compliant longitudinal measurements The Tumor Imaging Metrics Core of the Dana Farber Harvard Cancer Center has increased the quality and efficiency of imaging assessments by developing a software system branded Precision Imaging Metrics PIM which is currently in use at six NCI designated Cancer Centers The PIM system consists of two applications a web based workflow informatics management application and a desktop imaging application This proposal aims to extend the PIM solution into an entirely cloud based widely deployable and easily supportable system with an integrated web based image review tool The proposed contract has two aims to assess the feasibility of a cloud hosted zero footprint system for workflow management and image review and to develop systematic processes and documentation to simplify onboarding performance qualification and customer support of nationwide Cancer Centers A prototype will be created to identify obstacles to development and to determine areas of focus for Phase II implementation to address the goal of long term sustainability as a commercial entity