SBIR/STTR Research Award

OVEREXPRESSION OF A BACTERIA CHITINASE GENE IN PLANTS. A NOVEL APPROACH TO DISEASE TOLERANCE.

Award identifier 455fedeb7a7efbc3e624980ad33a3cf5faa67f9dc64c6e5d60bab721c624e87eAwarding agency National Science Foundation

Award amount

$243,000

Program and phase

SBIR · Phase II

Award year

1987

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Award details

Awarding agency
National Science Foundation
Branch
Not reported
Recipient company
Dna Plant Technologi
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

GENES SPECIFYING CHITINASE FROM SERRATIA MARCESCENS HAVE BEEN ISOLATED AND CHARACTERIZED. EVIDENCE THAT THIS PRODUCTIS INVOLVED IN THE CONTROL, BY THIS ORGANISM, OF CERTAIN FUNGAL DISEASES IS PROVIDED. THIS PROPOSAL DESCRIBES EXPERIMENTS IN WHICH THE REGULATORY ELEMENTS OF A PLANT GENESPECIFYING THE APOPROTEIN OF THE LIGHT HARVESTING COMPLEX ARE FUSED TO THE CODING PORTION OF A SERRATIA MARCESCENS CHITINASE GENE. THE CONSTRUCT WILL BE INTRODUCED INTO TOBACCO CELLS AND A POPULATION OF TRANSFORMED PLANTS REGENERATED AND TESTED FOR CHITINASE PRODUCTION. INDIVIDUAL CLONES SHOWING RELATIVELY HIGH LEVELS OF CHITINASE ACTIVITY WILL BE TESTED FOR THEIR SENSITIVITY TO THE FUNGAL PATHOGEN ALTERNARIA ALTERNATA.

Technology keywords

Not reported

Agency intelligence

National Science Foundation

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