Dedicated Nuclear Medicine Breast Imaging Device

Currently, mammography is an important tool in breast cancer screening and has been shown to reduceby early detection. Despite being a very sensitive technique, mammography's specificity is limited iapproximately 10-30% of mammographically-directed biopsies are positive. Both PET and single-photonimaging studies using Thallium-201, Technetium-99m Sestamibi, and F-18 Fluorodeoxyglucose have beenprovide sensitive and specific detection of breast cancers. Nuclear Medicine studies would provide cfor Secondary breast cancer screening by limiting the number of negative biopsies. For this purpose,Nuclear Medicine breast imaging device based on NaI(T1) detectors capable of performing both PET andstudies. Since both PET and single-photon radiotracers are likely to play a role in breast cancer deof imaging both tracers is ideally suited to the task. Besides improving the quality of breast imagiinstrumentation, this device should be sufficiently inexpensive to make Nuclear Medicine breast canceffective as a secondary screening method. In this Phase I application, we will study the feasibilitits overall design.