SBIR/STTR Research Award

Quantitative Tagged Antigen Magnetic Deposition

Award identifier 4e8b718a0cdad3815a2917ed31e92fb31ad707117c0271a80627a87e741c9664Awarding agency Department of Health and Human Services

Award amount

$99,043

Program and phase

SBIR · Phase I

Award year

1995

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
Institute Guilfoyle
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

This project is a feasibility study to demonstrate that Tagged Antigen Magnetic Deposition (TAMD) csuccessfully select and deposit tagged human lymphocytes on a microscope slide for analysis, countinstorage. Selective tagging and magnetic deposition of subpopulations of morphologically intact lymphinnovative and inexpensive technology suitable for wide distribution to clinical laboratories. Indivdrawn human lymphocytes tagged with CD specific monoclonal antibodies, polyclonal antibodies, avidinthrough a sealed delivery system and deposition channel over a magnetic gap. Tagged lymphocytes depoconcentrated group on a slide, where they can be stained, counted and preserved. The work will verifan innovative and inexpensive alternative to FACS flow cytometry for the detection of AIDS, immunodediseases and cancers. It will provide a mass screening tool for wide distribution throughout the medstudy will prove the feasibility of proceeding with work on TAMD for Phase II clinical trials and decommercial use of this technology.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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