SBIR/STTR Research Award
TOPIC 393: INTEGRATED PHOTONIC BIOSENSOR FOR PRECISION ONCOLOGY DOSE MEASUREMENTS
Award amount
$299,964Program and phase
SBIR · Phase IAward year
2019Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- INTELLIGENT FIBER OPTIC SYSTEMS CORP
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- HCXHVBD9HKN9
- Solicitation number
- Not reported
- Topic code
- NCI
Research abstract
Radiation therapy is a widely used primary treatment for multiple malignanciesHoweverphysical dose measurement is not an effective approach as the biological response of different patients or even different types of cancers are very different for the same physical doseMoreoverdiseased tissue and normal organ radiation sensitivities also varyExisting medical devicesphysical dosimetersdo not satisfy all the metrics for assessing biological response to radiation therapyespecially in a point of care mannerIFOS and Stanford University are developing a rapidportableeasy to use and quantitative dose measurement methodcomprising a portable handheld sensor and a novel nanoprobe for rapidreal time in situ imaging of cancerous tissueThe probe is designed to detect Reactive Oxygen and Nitrogen SpeciesRONSgenerated due to radiation and charge particle therapyThe innovation will provide greatly enhanced imaging capabilities to oncologists in radiation treatment monitoring
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Optical Gyro Distributed Temperature Compensation for Precision Orbital Power Beaming
- Ring Laser Gyroscope Operating at Exceptional Point with Extremely High Sensitivity
- High Flux Compact Strontium Source
- Subwavelength Surface Gratings for Ultra-Efficient Fiber-to-Photonic-IC Coupling
- Photonically Sensorized Robotic Subsurface Sampling System
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment
- Development of small molecule therapeutics targeting AR-V7 for prostate cancer
- Decentralized Clinical Trial of Effectiveness of EnergyPoints App to Guide Acupressure Use for Fatigue and Sleep Disturbances in Cancer Survivors
- Optimized targeted radiotherapy of pancreatic cancer
- Adaptive imaging for pioneering multiplexed spatial profiling of tumors and tissues for cancer research and diagnosis
Research funding history
172 SBIR/STTR records share this UEI (1994–2025). Reported award amounts total $61,008,158. Reported amounts are not federal obligations.
Phases: Phase I, Phase II, Phase II – Direct to Phase II
Agencies: Department of Defense, National Aeronautics and Space Administration, Department of Energy, Department of Health and Human Services, National Science Foundation, Department of Agriculture